Pressurized Intraperitoneal Aerosol Chemotherapy: The Road from Promise to Proof.

Loek A W de Jong Nielka P van Erp Lana Bijelic

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is an innovative drug delivery technique invented to be used for the treatment of peritoneal metastasis. Its application gained popularity over the past years. Several prospective clinical trials are being conducted to determine efficacy and safety. At this moment, there remain many challenges to overcome before PIPAC can be widely adopted in clinical practice.See related article by Kim et al., p. 1875.

Keyphrases

drug delivery
clinical trial
clinical practice
locally advanced
water soluble
cancer therapy
squamous cell carcinoma
randomized controlled trial
rectal cancer
big data
chemotherapy induced
combination therapy
radiation therapy
phase iii
artificial intelligence