Transcriptome resilience predicts thermotolerance in Caenorhabditis elegans.

Katharina JovicJacopo GrilliMark G SterkenBasten L SnoekJoost A G RiksenStefano AllesinaJan E Kammenga

Published in: BMC biology (2019)

Our findings imply that thermotolerance is an intrinsic property that pre-determines long-term outcome of stress and can be predicted by the transcriptional resilience parameter. Inferring the transcriptional resilience parameters of higher organisms could aid in evaluating rehabilitation strategies after stresses such as disease and trauma.

Keyphrases

heat shock
climate change
social support
gene expression
transcription factor
single cell
heat stress
rna seq
gram negative
heat shock protein
oxidative stress