Novel Vaccine Targeting Colonic Adenoma: a Pre-clinical Model.

Toan D PhamSandra CarpinteriShienny SampurnoLloyd PereiraSara RothVignesh NarasimhanPhillip DarcyJayesh DesaiAlexander G HeriotRobert G Ramsay

Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2019)

TetMYB vaccine has shown benefit in a prophylactic and therapeutic setting in the management of colonic adenoma in a murine model. This will form the basis for a future clinical trial to prevent and treat colonic adenomatous polyps.

Keyphrases

clinical trial
ulcerative colitis
cancer therapy
study protocol
open label
randomized controlled trial
phase ii
drug delivery
chronic rhinosinusitis