The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.

Wenwen WangKan Chen Yujing XiaWenhui MoFan WangWeiqi DaiPeiqin Niu

Published in: PPAR research (2018)

OA exhibits anti-inflammatory properties during ConA-induced acute liver injury by attenuating apoptosis and autophagy through activation of PPARα and downregulation of JNK signaling.

Keyphrases

cell death
signaling pathway
endoplasmic reticulum stress
anti inflammatory
oxidative stress
insulin resistance
induced apoptosis
cell cycle arrest
cell proliferation
ischemia reperfusion injury
fatty acid
knee osteoarthritis
pi k akt
skeletal muscle
cerebral ischemia
brain injury
subarachnoid hemorrhage