β 2-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese.

Mayuka NakajimaMichihiro HosojimaKoichi TabetaSayuri MiyauchiMiki Yamada-HaraNaoki TakahashiHaruna MiyazawaYumi Matsuda-MatsukawaKeisuke SatoNoriko SugitaYasutaka KomatsuTomomi IshikawaKazuhiro AkiishiKazuhisa YamazakiKiminori KatoAkihiko SaitoHiromasa Yoshie

Published in: International journal of dentistry (2019)

The significant association between urine β 2-MG or NGAL and periodontitis was revealed. These biomarkers can potentially be used to screen for or diagnose periodontitis. This trial is registered with the UMIN Clinical Trials Registry UMIN000013485.

Keyphrases

clinical trial
phase ii
phase iii
high throughput
study protocol
physical activity
single cell
randomized controlled trial
open label
risk assessment
double blind