A randomized, double-blind, placebo-controlled, pharmacogenetic study of ondansetron for treating alcohol use disorder.
Chamindi SeneviratneDavid A GorelickKevin G LynchClayton BrownDanielle RomerTimothy PondKyle KampmanHenry R KranzlerPublished in: Alcoholism, clinical and experimental research (2022)
We found no evidence that low-dose oral ondansetron is beneficial in the treatment of AUD, irrespective of genotype, thus failing to confirm prior study findings. However, the study was underpowered to identify medication by genotype interactions.