Deregulation of selected microRNAs in sinonasal carcinoma: Value of miR-21 as prognostic biomarker in sinonasal squamous cell carcinoma.

Helena KovaříkováIvana BubancovaJan LacoKaterina SieglovaHana VosmikovaMilan VosmikPavel DundrKristyna NemejcovaJaroslav MichalekVladimir PalickaMarcela Chmelarova

Published in: Head & neck (2017)

Our results suggest that miR-21 upregulation is involved in tumorigenesis of sinonasal carcinoma and that it is associated with poor prognosis. Thus, miR-21 could be used as a valuable prognostic biomarker.

Keyphrases

long non coding rna
poor prognosis
cell proliferation
squamous cell carcinoma
long noncoding rna
chronic rhinosinusitis
radiation therapy
lymph node metastasis