Expression of 15-lipoxygenase-1 in Merkel cell carcinoma is linked to advanced disease.
Alexandra Fochtmann-FranaGeorg HaymerleHelga SchachnerJohannes PammerRobert LoeweDontscho KerjaschkiChristos PerisanidisBoban M ErovicPublished in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2018)
In the current study, we were able to show ALOX15 expression in the primary MCC sample and the metastasis sample. Based on the findings of the current study, expression rate of ALOX15 in primary MCC and metastases is possibly linked to an increased lymphatic vessel density.