HepatoScore-14: Measures of Biological Heterogeneity Significantly Improve Prediction of Hepatocellular Carcinoma Risk.
Jeffrey S MorrisManal M HassanYe Emma ZohnerZeya WangLianchun XiaoAsif RashidAbedul HaqueReham Abdel-WahabYehia I MohamedKarri L BallardRobert A WolffBhawana GeorgeLiang LiGenevera AllenMichael WeylandtDonghui LiWenyi WangKanwal RaghavJames C YaoHesham M AminAhmed Omar KasebPublished in: Hepatology (Baltimore, Md.) (2021)
HepatoScore-14 augments existing HCC staging systems, dramatically refining patient prognostic assessments and therapeutic decision making and enrollment in clinical trials. The underlying strategy provides a global biological characterization of disease, and can be applied broadly to other disease settings and biological media.