Hamsters Are a Better Model System than Rats for Evaluating the Hypocholesterolemic Efficacy of Potential Probiotic Strains.

Chun-Feng GuoYa-Hong YuanTian-Li YueJing-Yan Li

Published in: Molecular nutrition & food research (2018)

These data suggest that the hypocholesterolemic efficacy of L. acidophilus K16 is substantially different between high-cholesterol-fed hamsters and rats and that hamsters are a better model system than rats for evaluating the hypocholesterolemic efficacy of potential probiotic strains due to their similarity to humans in biliary bile acid composition, including types of bile acids and their conjugation form.

Keyphrases

escherichia coli
bacillus subtilis
electronic health record
big data
machine learning
artificial intelligence