Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic population-based cohort study in Scotland, UK.
Ify R MordiBenjamin K ChanN David YanezColin Neil Alexander PalmerChim C LangJames D ChalmersPublished in: PLoS medicine (2020)
In this study, we observed that the increased risk of CV events with clarithromycin compared with amoxicillin was associated with an interaction with P-glycoprotein.