Molecular evolutionary analysis of human primary microcephaly genes.
Nashaiman PervaizHongen KangYiming BaoAmir Ali AbbasiPublished in: BMC ecology and evolution (2021)
Based on these data it can be inferred that protein-coding sequence of MCPH genes might not be the sole determinant of increase in relative brain size during primate evolutionary history.
Keyphrases
- genome wide
- dna methylation
- endothelial cells
- zika virus
- bioinformatics analysis
- genome wide identification
- intellectual disability
- white matter
- electronic health record
- amino acid
- resting state
- big data
- induced pluripotent stem cells
- pluripotent stem cells
- multiple sclerosis
- protein protein
- small molecule
- transcription factor
- brain injury
- subarachnoid hemorrhage