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Association of PD-L1 and IDO1 expression with JAK-STAT pathway activation in soft-tissue leiomyosarcoma.

Takeshi IwasakiKenichi KohashiYu TodaShin IshiharaYuichi YamadaYoshinao Oda
Published in: Journal of cancer research and clinical oncology (2020)
The results suggest the possible feasibility of the combined inhibition of PD-1/PD-L1 or IDO1 with IFN-γ-JAK-STAT pathway inhibition to treat soft tissue LMS.
Keyphrases
  • soft tissue
  • poor prognosis
  • immune response
  • dendritic cells
  • binding protein
  • long non coding rna