GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients.

Ulrike NeckmannCamilla WolowczykMartina HallEivind AlmaasJiang RenSen ZhaoBjarne JohannessenRolf I SkotheimGeir BjørkøyPeter Ten DijkeToril Holien

Published in: Cell communication and signaling : CCS (2019)

In conclusion, our results show that GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients. Gremlin1 could represent a novel target for therapy.

Keyphrases

poor prognosis
long non coding rna
estrogen receptor
endoplasmic reticulum
breast cancer cells
stem cells