Lessons learned from two clinical trials on nutritional supplements to reduce aggressive behaviour.
Nienke J de BlesDavid A A GastAbe J C van der SlotRobert DiddenAlbert M van HemertNathaly Rius OttenheimEric J GiltayPublished in: Journal of evaluation in clinical practice (2022)
By sharing these practical experiences, we hope to inform other researchers how to optimally design their trials, while avoiding and minimising the difficulties that we encountered, and to facilitate the implementation of a trial. Both trials were registered in the Clinical Trials Register (RCT A: NCT02498106; RCT B: NCT03212092).