The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma.

Chang-Won KangKatherine M HannanAnneke C BlackburnAmos H P LohKuick Chik HongGoh Jian YuanNadine HeinDenis DryginRoss D HannanLucy A Coupland

Published in: Investigational new drugs (2022)

SK-UT-1 was confirmed as a representative model of uterine leiomyosarcoma and CX-5461 has significant potential as a novel adjuvant for this rare cancer.

Keyphrases

papillary thyroid
early stage
squamous cell
transcription factor
cross sectional
lymph node metastasis
squamous cell carcinoma
risk assessment