Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial.

Daniel O Thomas-RüddelMichael BauerLuís Ferreira MoitaChristiane HelbigPeter SchlattmannJohannes EhlerTim RahmelPatrick MeybohmMatthias GründlingHeiko SchenkThomas KöcherFrank M BrunkhorstMarkus GrälerAnn-Julika HegerSebastian Weisnull nullnull null

Published in: BMJ open (2024)

NCT05033808.

Keyphrases

septic shock
placebo controlled
open label
study protocol
phase iii
double blind
phase ii
clinical trial
randomized controlled trial
acute kidney injury
phase ii study
intensive care unit
combination therapy
radiation therapy