Brown fat does not cause cachexia in cancer patients: A large retrospective longitudinal FDG-PET/CT cohort study.
Anton Sebastian BeckerCaroline ZellwegerSara BacanovicSabine FranckenbergHannes W NagelLukas FrickKhoschy SchawkatMatthias EberhardChristian BluethgenJörk VolbrachtRudolf MoosChristian WolfrumIrene Andrea BurgerPublished in: PloS one (2020)
Our data did not confirm the hypothesis that BAT plays a major role in cancer-mediated weight loss. Temperature changes are the main driver of incidental BAT activity on FDG-PET scans.
Keyphrases
- weight loss
- pet ct
- positron emission tomography
- computed tomography
- pet imaging
- cross sectional
- papillary thyroid
- bariatric surgery
- adipose tissue
- squamous cell
- electronic health record
- roux en y gastric bypass
- big data
- gastric bypass
- lymph node metastasis
- type diabetes
- machine learning
- magnetic resonance
- squamous cell carcinoma
- obese patients
- metabolic syndrome
- deep learning
- weight gain
- childhood cancer
- artificial intelligence
- glycemic control