Management of atypical chronic lymphocytic leukemia presenting with extreme leukocytosis.

Ramya MuddasaniNeel TalwarJaime Andres Suarez-LondonoMarc J Braunstein

Published in: Clinical case reports (2020)

Atypical chronic lymphocytic lymphoma (CLL) with CCND1 translocation is poorly described, particularly in the era of modern inhibitors of the B-cell receptor pathway. We present a patient with atypical CLL who had a significant response to ibrutinib, highlighting the effectiveness of this agent in higher risk CLL subgroups.

Keyphrases

chronic lymphocytic leukemia
case report
randomized controlled trial
systematic review
diffuse large b cell lymphoma
climate change
binding protein
drug induced