Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population.

Yuan LiShousheng LiuYuqiang GaoHuan MaShuhui ZhanYan YangYong-Ning XinShiying Xuan

Published in: BMC biochemistry (2019)

We demonstrated the significant association between TM6SF2 rs58542926 polymorphism and the risk of NAFLD and NAFLD&CRA in a Chinese Han population. The TM6SF2 rs58542926 T allele promotes the abnormal regulation of lipid profiles and liver injury in NAFLD patients, NAFLD&CRA patients, and overall subjects.

Keyphrases

end stage renal disease
liver injury
newly diagnosed
ejection fraction
chronic kidney disease
drug induced
prognostic factors
peritoneal dialysis
patient reported outcomes
fatty acid
liver fibrosis