Catheter ablation vs. antiarrhythmic drugs as 'first-line' initial therapy for atrial fibrillation: a pooled analysis of randomized data.
Shaojie ChenHelmut PürerfellnerFeifan OuyangMárcio Galindo KiuchiChristian MeyerMartin MartinekPiotr FutymaLin ZhuAlexandra SchratterJiazhi WangWillem-Jan AcouZhiyu LingYuehui YinShaowen LiuPhilipp SommerBoris SchmidtJulian K R ChunPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2022)
Catheter ablation as 'initial therapy' was superior to AADs in maintenance of sinus rhythm and improving QoL for patients with symptomatic paroxysmal AF, without increasing risk of serious adverse events.
Keyphrases
- catheter ablation
- atrial fibrillation
- left atrial
- left atrial appendage
- oral anticoagulants
- phase iii
- direct oral anticoagulants
- double blind
- open label
- heart failure
- percutaneous coronary intervention
- placebo controlled
- electronic health record
- big data
- phase ii
- clinical trial
- randomized controlled trial
- machine learning
- blood pressure
- coronary artery disease
- acute coronary syndrome
- drug induced
- study protocol
- mesenchymal stem cells
- artificial intelligence