Increased expression of angiopoietin-like protein 4 regulates matrix metalloproteinase-13 expression in Porphyromonas gingivalis lipopolysaccharides-stimulated gingival fibroblasts and ligature-induced experimental periodontitis.
Shun KondoKento KojimaNobuhisa NakamuraMegumi MiyabeTakeshi KikuchiTasuku OhnoNoritaka SawadaTomomi MinatoTomokazu SaikiMizuho ItoSachiko SasajimaTatsuaki MatsubaraAkio MitaniKeiko NarusePublished in: Journal of periodontal research (2022)
Periodontitis increases ANGPTL4 expression in the gingiva, further suggesting that increased ANGPTL4 may be a factor involved in enhancing MMP13 expression.