Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort Study.

Adrián Borja-FloresSalvador Israel Macías-Hernández Gabriela Hernandez-MolinaAndric Perez-OrtizEloy Reyes-MartínezJosé Belzazar-Castillo de la TorreLaura Ávila-JiménezMaría Cristina Vázquez-BelloMarco Antonio León-MazónJanette Furuzawa-Carballeda Gonzalo Torres-VillalobosFernanda Romero-HernándezCidronio Albavera-HernándezJesús Pérez-CorreaHilda A Castro-Rocha

Published in: Advances in orthopedics (2020)

Polymerized-collagen increased the time to TKR by at least 60 months, modifying the disease course, improving functional disability, and decreasing pain.

Keyphrases

knee osteoarthritis
chronic pain
wound healing
randomized controlled trial
tissue engineering
multiple sclerosis
systematic review
pain management
neuropathic pain
ultrasound guided