Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease.
Man LiuSamuel C DudleyPublished in: Antioxidants (Basel, Switzerland) (2020)
Hypomagnesemia is commonly observed in heart failure, diabetes mellitus, hypertension, and cardiovascular diseases. Low serum magnesium (Mg) is a predictor for cardiovascular and all-cause mortality and treating Mg deficiency may help prevent cardiovascular disease. In this review, we discuss the possible mechanisms by which Mg deficiency plays detrimental roles in cardiovascular diseases and review the results of clinical trials of Mg supplementation for heart failure, arrhythmias and other cardiovascular diseases.
Keyphrases
- cardiovascular disease
- heart failure
- oxidative stress
- clinical trial
- cardiovascular risk factors
- cardiovascular events
- type diabetes
- blood pressure
- left ventricular
- dna damage
- atrial fibrillation
- replacement therapy
- randomized controlled trial
- acute heart failure
- signaling pathway
- diabetic rats
- phase ii
- open label
- coronary artery disease
- study protocol