Proteomic signatures of physical, cognitive, and imaging outcomes in multiple sclerosis.
Kian JalaleddiniDejan JakimovskiAnisha KeshavanShannon McCurdyKelly LeydenFerhan QureshiAtiyeh GhoreyshiNiels P BergslandMichael G DwyerMurali RamanathanBianca Weinstock-GuttmanRalph Hb BenedictRobert ZivadinovPublished in: Annals of clinical and translational neurology (2024)
Multiple proteins, selected from a disease activity test that represent diverse biological pathways, are associated with physical, cognitive, and radiographic outcomes. Future studies should determine the utility of multiple protein assays in routine clinical care.
Keyphrases
- disease activity
- multiple sclerosis
- rheumatoid arthritis
- systemic lupus erythematosus
- physical activity
- rheumatoid arthritis patients
- mental health
- ankylosing spondylitis
- healthcare
- high resolution
- juvenile idiopathic arthritis
- palliative care
- high throughput
- quality improvement
- genome wide
- dna methylation
- mass spectrometry
- gene expression
- small molecule
- pain management
- protein protein
- insulin resistance
- chronic pain
- weight loss