Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer.
Michael CekayPhilipp F ArndtJohanna K FrankenJochen WilhelmSoni Savai PullamsettiFritz C RollerNatascha SommerIngolf AskevoldGerson LüdeckeChristine LangerMarco SteinFelix ZeppernickKhodr TelloUlf SibeliusFriedrich GrimmingerWerner SeegerSoni Savai PullamsettiBastian EulPublished in: BMJ open respiratory research (2024)
In this study, fewer patients with cancer had surrogate parameters for PH compared with previously published results among patients with lung cancer. Consequently, the prevalence of PH in other cancers might be lower compared with lung cancer; however, PH still has a negative impact on prognosis. Furthermore, our data does not provide evidence that lung metastases cause PH. Thus, our results support the idea that lung cancer-associated PH represents a new category of PH. Our results also highlight the importance of further studies in the field of cardio-oncology.