Exposure to Stress-Dose Steroids and Lethal Septic Shock After In-Hospital Cardiac Arrest: Individual Patient Data Reanalysis of Two Prior Randomized Clinical Trials that Evaluated the Vasopressin-Steroids-Epinephrine Combination Versus Epinephrine Alone.
Spyros D MentzelopoulosIosifina KoliantzakiMarios KarvouniarisCharikleia VrettouNicolas MongardonGeorge KarlisDemosthenes MakrisEpaminondas ZakynthinosSotirios SourlasStavros AloizosTheodoros XanthosSpyros G ZakynthinosPublished in: Cardiovascular drugs and therapy (2019)
In this reanalysis, exposure to stress-dose steroids (primarily in the context of a combined VSE intervention) was associated with lower risk of postresuscitation lethal septic shock.