The Effect of Fiber Supplementation on Chronic Constipation in Adults: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Alice van der Schoot Candice Drysdale Kevin Whelan Eirini Dimidi

Published in: The American journal of clinical nutrition (2022)

Fiber supplementation is effective at improving constipation. Particularly, psyllium, doses >10 g/d and treatment durations of at least 4 weeks appear optimal, though caution is needed when interpreting the results due to considerable heterogeneity. These findings provide promising evidence on the optimal type and regime of fiber supplementation, which could be used to standardize recommendations to patients. The protocol for this review is registered at PROSPERO as CRD42020191404.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
randomized controlled trial
peritoneal dialysis
irritable bowel syndrome
single cell
patient reported outcomes
clinical practice
combination therapy
preterm birth