Modulation of VIPergic phenotype of enteric neurons by colonic biopsy supernatants from patients with inflammatory bowel diseases: Involvement of IL-6 in Crohn's disease.

F SouffletM BiraudM Rolli-DerkinderenB LardeuxC TrangE CoronS Bruley des VarannesArnaud BourreilleM Neunlist

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)

Mucosal soluble factors from IBD induce VIP neuroplastic changes in the ENS. IL-6 was identified as a putative soluble factor responsible in part for changes in VIP expression in CD.

Keyphrases

ulcerative colitis
poor prognosis
spinal cord
ultrasound guided
long non coding rna
spinal cord injury