Low dose TamOxifen and LifestylE changes for bReast cANcer prevention (TOLERANT study): Study protocol of a randomized phase II biomarker trial in women at increased risk for breast cancer.

Aliana Guerrieri-GonzagaDavide SerranoPatrizia GnagnarellaHarriet JohanssonStefania ZovatoMariateresa NardiMatilde PensabeneSimona BuccoloAndrea DeCensiIrene Maria BriataLuigi PistelliClementina SansoneSara MannucciValentina AristarcoDebora MacisMatteo LazzeroniGaetano AurilioChiara Arianna AccorneroSara GandiniBernardo Bonanni

Published in: PloS one (2024)

EuCT number:2023-503994-39-00; Clinical trials.gov NCT06033092.

Keyphrases

phase ii
clinical trial
open label
study protocol
low dose
phase iii
double blind
placebo controlled
randomized controlled trial
breast cancer risk
polycystic ovary syndrome
physical activity
high dose
metabolic syndrome
weight loss
pregnancy outcomes
breast cancer cells
adipose tissue
young adults