Melatonin supplementation improves N-terminal pro-B-type natriuretic peptide levels and quality of life in patients with heart failure with reduced ejection fraction: Results from MeHR trial, a randomized clinical trial.

Shervin Ghaffari HoseiniKiyan Heshmat-GhahdarijaniSaeid KhosrawiMohammad GarakyaraghiDavood ShafieMarjan MansourianHamidreza RoohafzaElham AziziMasoumeh Sadeghi

Published in: Clinical cardiology (2022)

Oral melatonin decreased NT-Pro BNP and improved the quality of life in patients with HFrEF. Thus it might be a beneficial supplement in HFrEF.

Keyphrases

anti inflammatory
study protocol
clinical trial
phase iii
phase ii
randomized controlled trial