Expression of miR-15a, miR-145, and miR-182 in granulosa-lutein cells, follicular fluid, and serum of women with polycystic ovary syndrome (PCOS).
Mohammad NajiSaeid NekoonamAshraf AleyasinEhsan ArefianReza MahdianElham AziziMaryam Shabani NashtaeiFardin AmidiPublished in: Archives of gynecology and obstetrics (2017)
A significant dysregulation of miR-145 and miR-182 in GLCs of PCOS may indicate their involvement in pathogenesis of PCOS. Differential up-regulation of miR-182 in FF of PCOS patients with its promising predictive values for discrimination of PCOS reinforced the importance of studying miRNAs' profile in FF.