Pilot GWAS of caries in African-Americans shows genetic heterogeneity.

Ekaterina OrlovaJ C CarlsonM K LeeE FeingoldD W McNeilR J CroutR J WeyantM L MarazitaJ R Shaffer

Published in: BMC oral health (2019)

The genetic heterogeneity results suggest that there may be differences in the contributions of genetic variants to caries across racial groups, and highlight the critical need for the inclusion of minorities in subsequent and larger genetic studies of caries in order to meet the goals of precision medicine and to reduce oral health disparities.

Keyphrases

oral health
genome wide
single cell
copy number
randomized controlled trial
gene expression
study protocol