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SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen.

Lilibeth AriasKennedy OtwombeZiyaad WajaNestani TukvadzeTamta KorinteliTumelo MoloantoaKaori L FonsecaNatasha PillayThabiso SeiphetloDan Ouchi-VernetAdrian SilesLidia CarabiasCarles QuiñonesSergo VashakidzeNeil MartinsonCristina Vilaplana
Published in: Trials (2023)
Clinicaltrials.gov NCT04575519. Registered on October 5, 2020.
Keyphrases
  • double blind
  • placebo controlled
  • mycobacterium tuberculosis
  • clinical trial
  • phase iii
  • phase ii
  • study protocol
  • randomized controlled trial
  • open label
  • human health
  • bone marrow
  • drug induced
  • cell therapy