Intrauterine Malnutrition Reduced Long Leptin Receptor Isoform Expression and Proinflammatory Cytokine Production in Male Rat Pulmonary Endothelial Cells Stimulated by Lipopolysaccharide.
Aleksandro M BalbinoMarina M SilvaGabriela A AzevedoNoemi L GilRenaide R FerreiraLeila A Dos SantosRebéca M GasparinLiliam FernandesMaristella A LandgrafRichardt Gama LandgrafPublished in: Mediators of inflammation (2018)
These results suggest that intrauterine malnutrition compromises leptin receptor expression and cytokine production in pulmonary endothelial cells stimulated by LPS; these effects seem to involve the NF-κB and p38MAPK signaling pathways.