uMUC1-Targeting Magnetic Resonance Imaging of Therapeutic Response in an Orthotropic Mouse Model of Colon Cancer.

Hongwei ZhaoRomani RichardsonNazanin TaleblooPinku MukherjeePing WangAnna Moore

Published in: Molecular imaging and biology (2020)

We believe that in application to over 50 % of human cancers expressing uMUC1, our results could provide insight into overall assessment of therapeutic response based on its expression as defined by non-invasive MN-EPPT-enhanced MRI.

Keyphrases

magnetic resonance imaging
mouse model
contrast enhanced
endothelial cells
poor prognosis
cancer therapy
magnetic resonance
induced pluripotent stem cells
binding protein
drug delivery
room temperature
childhood cancer