A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population.
Bayram Cevdet AkdenizMorten MattingsdalMev Dominguez-ValentinOleksandr FreiAlexey ShadrinMikk PuustusmaaRegina SaarSiim SõberPål MøllerOle A AndreassenPeeter PadrikEivind HovigPublished in: Cancers (2023)
The previously validated PRS models have a similar observed accuracy in the Norwegian data as in the UK and Estonian populations. A PRS provides a meaningful association with the age of onset of BC and lifetime risk. Therefore, as suggested in Estonia, a PRS may also be integrated into the screening strategy for BC in Norway.