The Reduced Expression of EOLA1 May Be Related to Refractory Diabetic Foot Ulcer.

Mingxia WuWeilling Leng Hang PanXiaotian LeiChen LiuXinshou OuyangZiwen Liang

Published in: Mediators of inflammation (2019)

The refractory wounds in patients with DFU may be closely related to the uncontrolled activation of inflammatory pathways in cells caused by the reduced expression of negative regulators of inflammation (e.g., EOLA1), and such decreased expression may be also strongly linked to the persistent state of inflammation.

Keyphrases

poor prognosis
oxidative stress
induced apoptosis
binding protein
transcription factor
cell death
cell cycle arrest
signaling pathway