Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections.
Alfredo Jover-SáenzMaria F Ramirez-HidalgoAlba Bellés BellésEsther Ribes MurilloMeritxell Batlle BoschJosé Cayado CabanillasSònia Garrido-CalvoMaría Isabel Gracia VilasLaura Gros NavésMaría Jesús Javierre CaudevillaAlba Mari LópezLidia Montull NavarroMireia Ortiz VallsGemma Terrer ManriquePilar Vaqué CastillaJosé Javier Ichart TomásElena Justribó SánchezEster Andreu MayorJoan Carrera GuiuRoser Martorell SoléSilvia Pallàs SatuéMireia Saura CodinaAna Vena MartínezJosé Manuel Albalat SamperSusana Cano MarrónIsabel Chacón DomínguezDavid de la Rica EscuinMaría José Estadella ServallsAna M Figueres FarrenySonia Minguet VidalLuís Miguel Montaña EstebanJosep Otal BarecheMercè Pallerola PlanesFrancesc Pujol AymerichAndrés Rodríguez GarrochoAntoni Solé CurcóFrancisca Toribio RedondoMaría Cruz Urgelés CastillónJuan Valgañon PalaciosAlfredo Jover-Sáenznull The P-Ilehrda Groupnull On Behalf Of Translational Research Group On Infectious Diseases Of Lleida Head Group Tridle-IRBLleidaPublished in: Antibiotics (Basel, Switzerland) (2022)
Antimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of available data in these settings. We implemented an ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, compared to the pre-intervention period, a significant reduction in antibiotic prescription occurred, with a reduction in resistance in E. coli urinary isolates. ASP activities also were found to be cost-effective, with a reduction in medication prescription.