Effectiveness of COVID-19 Vaccines Over Time Prior to Omicron Emergence in Ontario, Canada: Test-Negative Design Study.

Hannah ChungPeter C AustinKevin A BrownSarah A BuchanDeshayne B FellCindy FongJonathan B GubbaySharifa NasreenKevin L SchwartzMaria E SundaramMina TadrousKumanan WilsonSarah E WilsonJeffrey C Kwong

Published in: Open forum infectious diseases (2022)

Before the emergence of Omicron, VE of any 2-dose primary series, including heterologous schedules and varying dosing intervals, decreased over time against any infection and symptomatic infection but remained high against severe outcomes.

Keyphrases

coronavirus disease
randomized controlled trial
systematic review
early onset
metabolic syndrome
skeletal muscle
insulin resistance
bacillus subtilis