Transcatheter aortic valve implantation for aortic stenosis in high surgical risk patients: A systematic review and meta-analysis.
Zulian LiuElaine KidneyDanai BemGeorge BramleySusan BaylissMark A de BelderPauline M ChristmasRui V DuartePublished in: PloS one (2018)
Symptomatic aortic stenosis can be lethal without intervention but surgical resection is contraindicated for some patients and high risk for others. We found that all-cause mortality up to 5 years of follow-up did not differ significantly between TAVI and SAVR in patients surgically operable at a high risk, but favoured TAVI over medical therapy in patients surgically inoperable. TAVI is a viable life-extending treatment option in these surgical high risk groups.
Keyphrases
- aortic stenosis
- ejection fraction
- transcatheter aortic valve implantation
- aortic valve
- aortic valve replacement
- transcatheter aortic valve replacement
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- left ventricular
- peritoneal dialysis
- randomized controlled trial
- healthcare
- coronary artery disease
- patient reported outcomes
- atrial fibrillation
- smoking cessation
- combination therapy