Genetic and early environmental predictors of adulthood self-reports of trauma.
Alicia J PeelKirstin L PurvesJessie R BaldwinGerome D BreenJonathan R I ColemanJean-Baptiste PingaultMegan SkeltonAbigail R Ter KuileAndrea DaneseThalia C EleyPublished in: The British journal of psychiatry : the journal of mental science (2022)
Genetic predisposition to ASD and PTSD may increase liability to experiencing or interpreting events as traumatic. Associations between genetic predisposition for risky behaviour and BMI with self-reported childhood trauma may reflect gene-environment correlation. Studies of the association between retrospectively self-reported childhood trauma and later-life outcomes should consider that genetically influenced reporter characteristics may confound associations, both directly and through gene-environment correlation.
Keyphrases
- genome wide
- copy number
- early life
- trauma patients
- dna methylation
- spinal cord injury
- autism spectrum disorder
- body mass index
- depressive symptoms
- attention deficit hyperactivity disorder
- genome wide identification
- emergency department
- gene expression
- childhood cancer
- risk assessment
- social support
- skeletal muscle
- physical activity
- adipose tissue
- transcription factor
- weight gain
- human health
- climate change
- adverse drug