Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Yangke CaiMeng ZhangXiaofu QiuBingwei WangYu FuJun ZengJian BaiGuosheng YangPublished in: Disease markers (2017)
Our findings demonstrate that upregulation of FBXW7 inhibits RCC metastasis and EMT. FBXW7 is a potential therapeutic target for RCC patients.
Keyphrases
- epithelial mesenchymal transition
- signaling pathway
- end stage renal disease
- poor prognosis
- renal cell carcinoma
- newly diagnosed
- cell proliferation
- transforming growth factor
- prognostic factors
- papillary thyroid
- peritoneal dialysis
- squamous cell carcinoma
- patient reported outcomes
- long non coding rna
- childhood cancer