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Phase I Study of Everolimus, Letrozole, and Trastuzumab in Patients with Hormone Receptor-positive Metastatic Breast Cancer or Other Solid Tumors.

Alexej BallhausenJennifer J WhelerDaniel D KarpSarina A Piha-PaulSiqing FuShubham PantApostolia M TsimberidouDavid S HongVivek SubbiahVeronica R HolleyHelen J HuangAbenaa M BrewsterKimberly B KoenigNuhad K IbrahimFunda Meric-BernstamFilip Janku
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Everolimus, letrozole, and trastuzumab have a favorable safety profile and elicit encouraging signals of anticancer activity in patients with heavily pretreated hormone receptor- and HER2-positive advanced cancers.
Keyphrases
  • metastatic breast cancer
  • polycystic ovary syndrome
  • epidermal growth factor receptor
  • early breast cancer
  • type diabetes
  • tyrosine kinase