David S Hong (David Hong)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 85

Top Topics

Advanced Cancer

Squamous Cell Carcinoma

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Nature medicine

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
David S Hong, Patricia LoRusso, Mario Sznol
A crisis in clinical research. Journal for immunotherapy of cancer 12 (7) (2024)
Ji Son, Yingao Zhang, Heather Y Lin, Oriol Mirallas, Pablo Álvarez Ballesteros, Mirella Nardo, Natalie Clark, Robert Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon Neville Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical and genomic landscape of RAS mutations in gynecologic cancers. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Vivek Subbiah, Niamh Coleman, Sarina A Piha-Paul, Apostolia-Maria Tsimberidou, Filip Janku, Jordi Rodon Ahnert, Shubham Pant, Ecaterina E Ileana Dumbrava, Siqing Fu, David S Hong, Shizhen Zhang, Ming Sun, Yunfang Jiang, Jason Roszik, Juhee Song, Ying Yuan, Funda Meric-Bernstam, Aung Naing
Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies. Cancer research communications 4 (2) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Brendan D Parent, Connor J Hennessey, Alexander C Jordan, Micaela Morgado, Shatavisha Dasgupta, Giselle A Uribe, Annan Yang, Kevin S Kapner, Felix P Hambitzer, Li Qiang, Hanrong Feng, Jacob Geisberg, Junning Wang, Kyle E Evans, Hengyu Lu, Aislyn Schalck, Ningping Feng, Anastasia M Lopez, Christopher A Bristow, Michael P Kim, Kimal I Rajapakshe, Vahid Bahrambeigi, Jennifer A Roth, Kavita Garg, Paola A Guerrero, Ben Z Stanger, Simona Cristea, Scott W Lowe, Timour Baslan, Eliezer Van Allen, Joseph D Mancias, Emily Chan, Abraham Anderson, Yuliya V Katlinskaya, Alex K Shalek, David S Hong, Shubham Pant, Jill Hallin, Kenna Anderes, Peter Olson, Timothy P Heffernan, Seema Chugh, James G Christensen, Anirban Maitra, Brian M Wolpin, Srivatsan Raghavan, Jonathan Andrew Nowak, Peter S Winter, Stephanie K Dougan, Andrew J Aguirre
Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer. Cancer discovery (2024)
Ji Son, Yingao Zhang, Heather Y Lin, Oriol Mirallas, Pablo Álvarez Ballesteros, Mirella Nardo, Natalie Clark, Robert Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon Neville Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical and genomic landscape of RAS mutations in gynecologic cancers. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Ji Son, Yingao Zhang, Heather Y Lin, Oriol Mirallas, Pablo Álvarez Ballesteros, Mirella Nardo, Natalie Clark, Robert Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon Neville Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical and genomic landscape of RAS mutations in gynecologic cancers. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Ji Son, Yingao Zhang, Heather Y Lin, Oriol Mirallas, Pablo Álvarez Ballesteros, Mirella Nardo, Natalie Clark, Robert Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon Neville Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical and Genomic Landscape of RAS Mutations in Gynecologic Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (14) (2024)
Ji Son, Yingao Zhang, Heather Y Lin, Oriol Mirallas, Pablo Álvarez Ballesteros, Mirella Nardo, Natalie Clark, Robert Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon Neville Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical and Genomic Landscape of RAS Mutations in Gynecologic Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (14) (2024)
Haniel A Araujo, Ximo Pechuan, Teng Zhou, Minh Truong Do, Xin Hu, Frank R Rojas Alvarez, Maria E Salvatierra, Heladio P Ibarguen, Richard Lee, Rashi Raghulan, Harshit Shah, Mariela A Moreno Ayala, Kevin Chen, Nataliya Tovbis Shifrin, Shuhong Wu, Luisa Maren Solis Soto, Marcelo Vailati Negrão, Don L Gibbons, David S Hong, Jack A Roth, John Victor Heymach, Jianjun Zhang, Jingjing Jiang, Mallika Singh, Jacqueline A M Smith, Elsa Quintana, Ferdinandos Skoulidis
Mechanisms of response and tolerance to active RAS inhibition in KRAS-mutant NSCLC. Cancer discovery (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Vivek Subbiah, Niamh Coleman, Sarina A Piha-Paul, Apostolia-Maria Tsimberidou, Filip Janku, Jordi Rodon Ahnert, Shubham Pant, Ecaterina E Ileana Dumbrava, Siqing Fu, David S Hong, Shizhen Zhang, Ming Sun, Yunfang Jiang, Jason Roszik, Juhee Song, Ying Yuan, Funda Meric-Bernstam, Aung Naing
Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies. Cancer research communications 4 (2) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
David S Hong, Patricia LoRusso, Mario Sznol
A crisis in clinical research. Journal for immunotherapy of cancer 12 (7) (2024)
David S Hong, Patricia LoRusso, Mario Sznol
A crisis in clinical research. Journal for immunotherapy of cancer 12 (7) (2024)
Niamh Coleman, Kathrina L Marcelo, Julia F Hopkins, Nusrat Israr Khan, Robyn R Du, Lingzhi Hong, Edward Park, Binaifer Balsara, Mollie Leoni, Curtis R Pickering, Jeffrey N Myers, John Victor Heymach, Lee A Albacker, David S Hong, Maura Gillison, Xiuning Li
HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma. JCO precision oncology 7 (2023)
Roberto Carmagnani Pestana, Justin Tyler Moyers, Jason Roszik, Shiraj Sen, David S Hong, Aung Naing, Cynthia E Herzog, Siqing Fu, Sarina A Piha-Paul, Jordi Rodon Ahnert, Timothy Anthony Yap, Daniel D Karp, Apostolia-Maria Tsimberidou, Shubham Pant, Maria Alejandra Zarzour, Ravin Ratan, Vinod Ravi, Robert S Benjamin, Alexander J F Lazar, Wei-Lien Wang, Najat C Daw, Jonathan D Gill, Douglas J Harrison, Valerae O Lewis, Christina Lynn Roland, Shreyaskumar R Patel, Jonathan A Livingston, Neeta Somaiah, Joseph A Ludwig, Anthony P Conley, Nelson Hammerschlak, Richard G Gorlick, Funda Meric-Bernstam, Vivek Subbiah
Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine 29 (1) (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
Raffit Hassan, Marcus O Butler, Roisin E O'Cearbhaill, David Y Oh, Melissa Lynne Johnson, Kevin Zikaras, Munisha Smalley, Michael Ross, Janos L Tanyi, Azam Ghafoor, Nirali N Shah, Babak Saboury, Liang Cao, Alfonso Quintás-Cardama, David S Hong
Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results. Nature medicine (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine 29 (1) (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine 29 (1) (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (9) (2023)
David S Hong, Michael A Postow, Bartosz Chmielowski, Ryan J Sullivan, Amita Patnaik, Ezra E W Cohen, Geoffrey I Shapiro, Conor E Steuer, Martin Gutierrez, Heather Yeckes-Rodin, Robert Ilaria, Brenda C O'Connell, Joanna Peng, Guangbin Peng, Nora Zizlsperger, Anthony W Tolcher, Jedd D Wolchok
Eganelisib, a First-in-Class PI3K-γ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (9) (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine 29 (1) (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Grace K Dy, Ramaswamy Govindan, Vamsidhar Velcheti, Gerald S Falchook, Antoine Italiano, Juergen Wolf, Adrian G Sacher, Toshiaki Takahashi, Suresh R Ramalingam, Christophe Dooms, Dong Wan Kim, Alfredo Addeo, Jayesh Desai, Martin Schuler, Pascale Tomasini, David S Hong, Piro Lito, Qui Tran, Simon Jones, Abraham Anderson, Antreas Hindoyan, Wendy Snyder, Ferdinandos Skoulidis, Bob T Li
Long-Term Outcomes and Molecular Correlates of Sotorasib Efficacy in Patients With Pretreated KRAS G12C-Mutated Non-Small-Cell Lung Cancer: 2-Year Analysis of CodeBreaK 100. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (9) (2023)
Niamh Coleman, Kathrina L Marcelo, Julia F Hopkins, Nusrat Israr Khan, Robyn R Du, Lingzhi Hong, Edward Park, Binaifer Balsara, Mollie Leoni, Curtis R Pickering, Jeffrey N Myers, John Victor Heymach, Lee A Albacker, David S Hong, Maura Gillison, Xiuning Li
HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma. JCO precision oncology 7 (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine 29 (1) (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (9) (2023)
Mrinal M Gounder, Todd M Bauer, Gary K Schwartz, Amy M Weise, Patricia LoRusso, Prasanna Kumar, Ben Tao, Ying Hong, Parul Patel, Yasong Lu, Arnaud Lesegretain, Vijaya G Tirunagaru, Feng Xu, Robert C Doebele, David S Hong
A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (9) (2023)
Niamh Coleman, Kathrina L Marcelo, Julia F Hopkins, Nusrat Israr Khan, Robyn R Du, Lingzhi Hong, Edward Park, Binaifer Balsara, Mollie Leoni, Curtis R Pickering, Jeffrey N Myers, John Victor Heymach, Lee A Albacker, David S Hong, Maura Gillison, Xiuning Li
HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma. JCO precision oncology 7 (2023)
Niamh Coleman, Kathrina L Marcelo, Julia F Hopkins, Nusrat Israr Khan, Robyn R Du, Lingzhi Hong, Edward Park, Binaifer Balsara, Mollie Leoni, Curtis R Pickering, Jeffrey N Myers, John Victor Heymach, Lee A Albacker, David S Hong, Maura Gillison, Xiuning Li
HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma. JCO precision oncology 7 (2023)
Vivek Subbiah, Niamh Coleman, Sarina A Piha-Paul, Apostolia-Maria Tsimberidou, Filip Janku, Jordi Rodon Ahnert, Shubham Pant, Ecaterina E Ileana Dumbrava, Siqing Fu, David S Hong, Shizhen Zhang, Ming Sun, Yunfang Jiang, Jason Roszik, Juhee Song, Ying Yuan, Funda Meric-Bernstam, Aung Naing
Phase I study of mTORC1/2 inhibitor sapanisertib in combination with metformin in patients with mTOR/AKT/PI3K pathway alterations and advanced solid malignancies. Cancer research communications (2023)
Marcelo Vailati Negrão, Haniel A Araujo, Giuseppe Lamberti, Alissa J Cooper, Neal S Akhave, Teng Zhou, Lukas Delasos, J Kevin Hicks, Mihaela Aldea, Gabriele Minuti, Jacobi Hines, Jacqueline V Aredo, Michael J Dennis, Turja Chakrabarti, Susan C Scott, Paolo Bironzo, Matthias Scheffler, Petros Christopoulos, Albrecht Stenzinger, Jonathan W Riess, So Yeon Kim, Sarah B Goldberg, Mingjia Li, Qi Wang, Yun Qing, Ying Ni, Minh Truong Do, Richard Lee, Biagio Ricciuti, Joao M Victor Alessi, Jing Wang, Blerina Resuli, Lorenza Landi, Shu-Chi Tseng, Mizuki Nishino, Subba R Digumarthy, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Ara A Vaporciyan, George R Blumenschein, Jianjun Zhang, Dwight H Owen, Collin M Blakely, Giannis S Mountzios, Catherine A Shu, Christine M Bestvina, Marina-Chiara Garassino, Kristen A Marrone, Jhanelle E Gray, Sandip Pravin Patel, Amy L Cummings, Heather A Wakelee, Juergen Wolf, Giorgio Vittorio Scagliotti, Federico Cappuzzo, Fabrice Barlesi, Pradnya D Patil, Leylah Drusbosky, Don L Gibbons, Funda Meric-Bernstam, Jiun-Kae Jack Lee, John Victor Heymach, David S Hong, Rebecca S Heist, Mark M Awad, Ferdinandos Skoulidis
Co-mutations and KRAS G12C inhibitor efficacy in advanced NSCLC. Cancer discovery (2023)
David S Hong, Brian Andrew Van Tine, Swethajit Biswas, Cheryl McAlpine, Melissa L Johnson, Anthony J Olszanski, Jeffrey M Clarke, Dejka Araujo, George R Blumenschein, Partow Kebriaei, Quan Lin, Alex J Tipping, Joseph P Sanderson, Ruoxi Wang, Trupti Trivedi, Thejo Annareddy, Jane Bai, Stavros Rafail, Amy Sun, Lilliam Fernandes, Jean-Marc Navenot, Frederic D Bushman, John K Everett, Derin Karadeniz, Robyn Broad, Martin Isabelle, Revashnee Naidoo, Natalie Bath, Gareth Betts, Zohar Wolchinsky, Dzmitry G Batrakou, Erin Van Winkle, Erica Elefant, Armin Ghobadi, Amanda Cashen, Anne Grand'Maison, Philip McCarthy, Paula M Fracasso, Elliot Norry, Dennis Williams, Mihaela Druta, David A Liebner, Kunle Odunsi, Marcus O Butler
Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A*02 + patients: a phase 1 trial. Nature medicine (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine (2023)
Kyaw Zin Thein, Amadeo B Biter, Kimberly C Banks, Andrew W Duda, Jennifer Saam, Jason Roszik, Filip Janku, Ferdinandos Skoulidis, John Victor Heymach, Edmund S Kopetz, Funda Meric-Bernstam, David S Hong
Identification of KRAS G12C Mutations in Circulating Tumor DNA in Patients With Cancer. JCO precision oncology 6 (2022)
Neal S Akhave, Amadeo B Biter, David S Hong
The Next Generation of KRAS Targeting: Reasons for Excitement and Concern. Molecular cancer therapeutics 21 (11) (2022)
Justin Tyler Moyers, Roberto Carmagnani Pestana, Jason Roszik, David S Hong, Aung Naing, Siqing Fu, Sarina A Piha-Paul, Timothy Anthony Yap, Daniel D Karp, Jordi Rodon Ahnert, Jonathan A Livingston, Maria Alejandra Zarzour, Vinod Ravi, Shreyaskumar R Patel, Robert S Benjamin, Joseph A Ludwig, Cynthia E Herzog, Ravin Ratan, Neeta Somaiah, Anthony P Conley, Richard G Gorlick, Funda Meric-Bernstam, Vivek Subbiah
Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102). Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Brian P Hobbs, Roberto Carmagnani Pestana, Emily C Zabor, Alexander M Kaizer, David S Hong
Basket Trials: Review of Current Practice and Innovations for Future Trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (30) (2022)
Kanwal P Raghav, Bettzy Stephen, Daniel D Karp, Sarina A Piha-Paul, David S Hong, Dipti Jain, Dilichukwu O Chudy Onwugaje, Abdulrahman Abonofal, Anneleis F Willett, Michael Overman, Brandon Smaglo, Ryan W Huey, Funda Meric-Bernstam, Gauri R Varadhachary, Aung Naing
Efficacy of pembrolizumab in patients with advanced cancer of unknown primary (CUP): a phase 2 non-randomized clinical trial. Journal for immunotherapy of cancer 10 (5) (2022)
Mohamed A Gouda, Helen J Huang, Sarina A Piha-Paul, S Greg Call, Daniel D Karp, Siqing Fu, Aung Naing, Vivek Subbiah, Shubham Pant, Derek J Dustin, Apostolia-Maria Tsimberidou, David S Hong, Jordi Rodon Ahnert, Funda Meric-Bernstam, Filip Janku
Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment Outcomes in Advanced Cancers. JCO precision oncology 6 (2022)
Patrick Schöffski, Daniel S W Tan, Miguel Martín, María Ochoa-de-Olza, John Sarantopoulos, Richard D Carvajal, Chrisann Kyi, Taito Esaki, Amy Prawira, Wallace Akerley, Filippo De Braud, Rina Hui, Tian Zhang, Ross A Soo, Michela Maur, Andrew Weickhardt, Jürgen Krauss, Barbara Deschler-Baier, Allen Lau, Tanay S Samant, Tyler Longmire, Niladri Roy Chowdhury, Catherine A Sabatos-Peyton, Nidhi Patel, Radha Ramesh, Tiancen Hu, Ana Carion, Daniel Gusenleitner, Padmaja Yerramilli-Rao, Vasileios Askoxylakis, Eunice L Kwak, David S Hong
Phase I/II study of the LAG-3 inhibitor ieramilimab (LAG525) ± anti-PD-1 spartalizumab (PDR001) in patients with advanced malignancies. Journal for immunotherapy of cancer 10 (2) (2022)
Uri Greenbaum, Ecaterina E Ileana Dumbrava, Amadeo B Biter, Cara L Haymaker, David S Hong
Engineered T-cell Receptor T Cells for Cancer Immunotherapy. Cancer immunology research 9 (11) (2022)
D Ross Camidge, Fabrice Barlesi, Jonathan Wade Goldman, Daniel Morgensztern, Rebecca S Heist, Everett E Vokes, Alexander I Spira, Eric Angevin, Wu-Chou Su, David S Hong, John H Strickler, Monica Motwani, Martin Dunbar, Apurvasena Parikh, Elysa Noon, Vincent Blot, Jun Wu, Karen Kelly
Phase Ib Study of Telisotuzumab Vedotin in Combination With Erlotinib in Patients With c-Met Protein-Expressing Non-Small-Cell Lung Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Aparna Hegde, Priyamvada Jayaprakash, Coline A Couillault, Sarina Piha-Paul, Daniel Karp, Jordi Rodon, Shubham Pant, Siqing Fu, Ecaterina E Dumbrava, Timothy Anthony Yap, Vivek Subbiah, Priya R Bhosale, Cristian Coarfa, Jack P Higgins, Eric T Williams, Thomas F Wilson, JoAnn Lim, Funda Meric-Bernstam, Elizabeth Sumner, Hira Zain, Di Nguyen, Ly M Nguyen, Kimal Rajapakshe, Michael A Curran, David S Hong
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (11) (2021)
David S Hong, Kathleen M Moore, Johanna C Bendell, Daniel D Karp, Judy S Wang, Susanna V Ulahannan, Suzanne F Jones, Wenjuan Wu, Gregory P Donoho, Yan Ding, Andrew Capen, Aimee Bence Lin, Manish R Patel
Preclinical Evaluation and Phase Ib Study of Prexasertib, a CHK1 Inhibitor, and Samotolisib (LY3023414), a Dual PI3K/mTOR Inhibitor. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (7) (2021)
D Ross Camidge, Daniel Morgensztern, Rebecca S Heist, Minal Barve, Everett E Vokes, Jonathan Wade Goldman, David S Hong, Todd M Bauer, John H Strickler, Eric Angevin, Monica Motwani, Apurvasena Parikh, Zhaowen Sun, Bruce Allen Bach, Jun Wu, Philip B Komarnitsky, Karen Kelly
Phase I Study of 2- or 3-Week Dosing of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, Monotherapy in Patients with Advanced Non-Small Cell Lung Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (21) (2021)
Mansoor N Saleh, Manish R Patel, Todd M Bauer, Sanjay Goel, Gerald S Falchook, Geoffrey I Shapiro, Ki Y Chung, Jeffrey R Infante, Robert M Conry, Guilherme Rabinowits, David S Hong, Judy S Wang, Ulrich Steidl, Gurudatta Naik, Vincent Guerlavais, Vojislav Vukovic, D Allen Annis, Manuel Aivado, Funda Meric-Bernstam
Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-Type TP53. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
David S Hong, Olivier Rixe, Vi K Chiu, Patrick M Forde, Tomislav Dragovich, Yanyan Lou, Asha Nayak-Kapoor, Rom S Leidner, James N Atkins, Agron Collaku, Floyd E Fox, Margaret A Marshall, Anthony J Olszanski
Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Neal S Akhave, Amadeo B Biter, David S Hong
Mechanisms of Resistance to KRASG12C-Targeted Therapy. Cancer discovery 11 (6) (2021)
Theodore W Laetsch, David S Hong
Tropomyosin Receptor Kinase Inhibitors for the Treatment of TRK Fusion Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (18) (2021)
Raymond U Osarogiagbon, Diana Merino Vega, Lola A Fashoyin-Aje, Suparna Wedam, Gwynn Ison, Sol Atienza, Peter De Porre, Tithi Biswas, Jamie N Holloway, David S Hong, Madison M Wempe, Richard L Schilsky, Edward S Kim, James L Wade
Modernizing Clinical Trial Eligibility Criteria: Recommendations of the ASCO-Friends of Cancer Research Prior Therapies Work Group. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (9) (2021)
Xiuning Li, Lingzhi Hong, Charles H Hensel, Rongrong Chen, Haley Kemp, Niamh Coleman, Christine A Ciunci, Stephen V Liu, Marcelo V Negrao, Jennifer Yen, Xuefeng Xia, Juergen Scheuenpflug, Christopher Stroh, Dilafruz Juraeva, Anne S Tsao, David S Hong, Victoria M Raymond, Paul K Paik, Jianjun Zhang, John V Heymach
Landscape and Clonal Dominance of Co-occurring Genomic Alterations in Non-Small-Cell Lung Cancer Harboring MET Exon 14 Skipping. JCO precision oncology 5 (2021)
Filip Janku, Halle Huihong Zhang, Abdulmohammad Pezeshki, Sanjay Goel, Ravi Murthy, Andrea Wang-Gillam, Dale R Shepard, Thorunn Helgason, Tyler Masters, David S Hong, Sarina A Piha-Paul, Daniel D Karp, Mark G Klang, Steven Y Huang, Divya Sakamuri, Anjali Raina, Jean Torrisi, Stephen B Solomon, Alice Weissfeld, Ernest Trevino, Gary DeCrescenzo, Amanda Collins, Maria Miller, Jennifer L Salstrom, Ronald L Korn, Linping Zhang, Saurabh Saha, Alexey A Leontovich, David Tung, Brent L Kreider, Mary Varterasian, Khashayarsha Khazaie, Mrinal M Gounder
Intratumoral Injection of Clostridium novyi-NT Spores in Patients with Treatment-refractory Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (1) (2020)
Vivek Subbiah, William Erwin, Osama Mawlawi, Asa McCoy, David Wages, Catherine Wheeler, Carlos Gonzalez-Lepera, Holly Liu, Homer Macapinlac, Funda Meric-Bernstam, David S Hong, Shubham Pant, Dao Le, Elmer Santos, Jose Gonzalez, Jason Roszik, Takeaki Suzuki, Ruth Ann Subach, Timothy Madden, Mary J Johansen, Fumiko Nomura, Hirokazu Satoh, Tadashi Matsuura, Masamichi Kajita, Eri Nakamura, Yuichi Funase, Satoshi Matsushima, Gregory Ravizzini
Phase I Study of P-cadherin-targeted Radioimmunotherapy with 90Y-FF-21101 Monoclonal Antibody in Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (22) (2020)
Dmitriy Zamarin, Omid Hamid, Asha Nayak-Kapoor, Solmaz Sahebjam, Mario Sznol, Agron Collaku, Floyd E Fox, Margaret A Marshall, David S Hong
Mogamulizumab in Combination with Durvalumab or Tremelimumab in Patients with Advanced Solid Tumors: A Phase I Study. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (17) (2020)
Ashvin R Jaiswal, Arthur J Liu, Shivanand Pudakalakatti, Prasanta Dutta, Priyamvada Jayaprakash, Todd Bartkowiak, Casey R Ager, Zhi-Qiang Wang, Alexandre Reuben, Zachary A Cooper, Cristina Ivan, Zhenlin Ju, Felix Nwajei, Jing Wang, Michael A Davies, R Eric Davis, Jennifer A Wargo, Pratip K Bhattacharya, David S Hong, Michael A Curran
Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype. Cancer immunology research 8 (11) (2020)
Joseph D Butner, Dalia Elganainy, Charles X Wang, Zhihui Wang, Shu-Hsia Chen, Nestor F Esnaola, Renata Pasqualini, Wadih Arap, David S Hong, James Welsh, Eugene Jon Koay, Vittorio Cristini
Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy. Science advances 6 (18) (2020)
Timothy Anthony Yap, David Shao Peng Tan, Angelika Terbuch, Reece Caldwell, Christina Guo, Boon Cher Goh, Heong Valerie Yue Ming, Noor R Md Haris, Saira Bashir, Yvette Drew, David S Hong, Funda Meric-Bernstam, Gary Wilkinson, Joseph Hreiki, Antje M Wengner, Friedhelm Bladt, Andreas Schlicker, Matthias Ludwig, Yinghui Zhou, Li Liu, Sonal Bordia, Ruth Plummer, Eleni Lagkadinou, Johann S de Bono
First-in-Human Trial of the Oral Ataxia Telangiectasia and RAD3-Related (ATR) Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors. Cancer discovery 11 (1) (2020)
Omar Alhalabi, Andrew W Hahn, Pavlos Msaouel, Alexander Y Andreev-Drakhlin, Funda Meric-Bernstam, Aung Naing, Sarina Piha-Paul, Filip Janku, Shubham Pant, Timothy Anthony Yap, David S Hong, Siqing Fu, Daniel Karp, Matthew T Campbell, Hung Le, Amishi Y Shah, Nizar M Tannir, Arlene O Siefker-Radtke, Jianjun Gao, Jason Roszik, Vivek Subbiah
Molecular Profiling of Metastatic Bladder Cancer Early-Phase Clinical Trial Participants Predicts Patient Outcomes. Molecular cancer research : MCR 19 (3) (2020)
Filip Janku, Haeseong Park, S Greg Call, Kiran Madwani, Yasuhiro Oki, Vivek Subbiah, David S Hong, Aung Naing, Vivianne M Velez-Bravo, Tamara G Barnes, Fredrick B Hagemeister, Gerald S Falchook, Daniel D Karp, Jennifer J Wheler, Sarina A Piha-Paul, Ignacio Garrido-Laguna, Elizabeth J Shpall, Luis E Fayad, Sattva S Neelapu, Funda Meric-Bernstam, Razelle Kurzrock, Michelle A Fanale
Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (21) (2020)
Roman Groisberg, Jason Roszik, Anthony P Conley, Alexander J F Lazar, Daniella E Portal, David S Hong, Aung Naing, Cynthia E Herzog, Neeta Somaiah, Maria Alejandra Zarzour, Shreyaskumar Patel, Robert E Brown, Vivek Subbiah
Genomics, Morphoproteomics, and Treatment Patterns of Patients with Alveolar Soft Part Sarcoma and Response to Multiple Experimental Therapies. Molecular cancer therapeutics 19 (5) (2020)
Shumei Kato, Ryosuke Okamura, Jason K Sicklick, Gregory A Daniels, David S Hong, Aaron Goodman, Elizabeth Weihe, Suzanna Lee, Noor Khalid, Rachel Collier, Manvita Mareboina, Paul Riviere, Theresa J Whitchurch, Paul T Fanta, Scott M Lippman, Razelle Kurzrock
Prognostic implications of RAS alterations in diverse malignancies and impact of targeted therapies. International journal of cancer 146 (12) (2020)
Alexej Ballhausen, Jennifer J Wheler, Daniel D Karp, Sarina A Piha-Paul, Siqing Fu, Shubham Pant, Apostolia M Tsimberidou, David S Hong, Vivek Subbiah, Veronica R Holley, Helen J Huang, Abenaa M Brewster, Kimberly B Koenig, Nuhad K Ibrahim, Funda Meric-Bernstam, Filip Janku
Phase I Study of Everolimus, Letrozole, and Trastuzumab in Patients with Hormone Receptor-positive Metastatic Breast Cancer or Other Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (5) (2020)
Goldy C George, Eucharia C Iwuanyanwu, Adrianna S Buford, Sarina A Piha-Paul, Vivek Subbiah, Siqing Fu, Daniel D Karp, Shubham Pant, Christina O Hinojosa, Kenneth R Hess, Charles S Cleeland, Elmer V Bernstam, Funda Meric-Bernstam, David S Hong
Cancer-Related Internet Use and Its Association With Patient Decision Making and Trust in Physicians Among Patients in an Early Drug Development Clinic: A Questionnaire-Based Cross-Sectional Observational Study. Journal of medical Internet research 21 (3) (2019)
David S Hong, Nicole Concin, Ignace Vergote, Johann S de Bono, Brian M Slomovitz, Yvette Drew, Hendrik-Tobias Arkenau, Jean-Pascal Machiels, James F Spicer, Robert Jones, Martin D Forster, Nathalie Cornez, Christine Gennigens, Melissa L Johnson, Fiona C Thistlethwaite, Reshma A Rangwala, Srinivas Ghatta, Kristian Windfeld, Jeffrey R Harris, Ulrik Niels Lassen, Robert L Coleman
Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (6) (2019)
James W Welsh, Chad Tang, Patricia M de Groot, Aung Naing, Kenneth R Hess, John Victor Heymach, Vassiliki A Papadimitrakopoulou, Taylor R Cushman, Vivek Subbiah, Joe Y Chang, George R Simon, Rishab Ramapriyan, Hampartsoum B Barsoumian, Hari Menon, Maria Angelica Cortez, Erminia Massarelli, Quynh Nguyen, Padmanee Sharma, James P Allison, Adi Diab, Vivek Verma, Uma Raju, Sherif G Shaaban, Ramona Dadu, Maria E Cabanillas, Kelvin Wang, Clark Anderson, Daniel R Gomez, Stephen Hahn, Ritsuko Komaki, David S Hong
Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses. Cancer immunology research 7 (12) (2019)
Seyed Pairawan, Kenneth R Hess, Filip Janku, Nora S Sanchez, Kenna R Mills Shaw, Cathy Eng, Senthilkumar Damodaran, Milind Javle, Ahmed O Kaseb, David S Hong, Vivek Subbiah, Siqing Fu, David R Fogelman, Victoria M Raymond, Richard B Lanman, Funda Meric-Bernstam
Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (8) (2019)
Ryan J Sullivan, Antoine Hollebecque, Keith T Flaherty, Geoffrey I Shapiro, Jordi Rodon Ahnert, Michael J Millward, Wei Zhang, Ling Gao, Amanda Sykes, Melinda D Willard, Danni Yu, Andrew E Schade, KrisAnne Crowe, Daniel L Flynn, Michael D Kaufman, James R Henry, Sheng-Bin Peng, Karim A Benhadji, Ilaria Conti, Michael S Gordon, Ramon V Tiu, David S Hong
A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer. Molecular cancer therapeutics 19 (2) (2019)
Gerald S Falchook, Razelle Kurzrock, Hesham M Amin, Wenyuan Xiong, Siqing Fu, Sarina A Piha-Paul, Filip Janku, Ghazaleh Eskandari, Daniel V Catenacci, Manfred Klevesath, Rolf Bruns, Uz Stammberger, Andreas Johne, Friedhelm Bladt, Manja Friese-Hamim, Pascal Girard, Samer El Bawab, David S Hong
First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (6) (2019)
Ignacio Garrido-Laguna, Ian Krop, Howard A Burris, Erika Hamilton, Fadi Braiteh, Amy M Weise, Maysa Abu-Khalaf, Theresa L Werner, Steven Pirie-Shepherd, Christopher J Zopf, Mani Lakshminarayanan, Jaymes S Holland, Raffaele Baffa, David S Hong
First-in-human, phase I study of PF-06647263, an anti-EFNA4 calicheamicin antibody-drug conjugate, in patients with advanced solid tumors. International journal of cancer 145 (7) (2019)
Amita Patnaik, Michael Gordon, Frank Tsai, Kyriakos P Papadopoulos, Drew Rasco, Muralidhar Beeram, Siqing Fu, Filip Janku, Scott M Hynes, Sushma R Gundala, Melinda D Willard, Wei Zhang, Aimee Bence Lin, David S Hong
A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer. Cancer chemotherapy and pharmacology 82 (3) (2018)