The effect of faecal microbiota transplantation on abdominal pain, stool frequency, and stool form in patients with moderate-to-severe irritable bowel syndrome: results from a randomised, double-blind, placebo-controlled study.
Anna Maria Alcasid MadsenSofie Ingdam HalkjærAlice Højer ChristensenStig GüntherPatrick Denis BrowneThomas KallemoseLars Hestbjerg HansenAndreas Munk PetersenPublished in: Scandinavian journal of gastroenterology (2021)
In this analysis of results from a randomised, double-blind, placebo-controlled study, we found no clinically beneficial effect of FMT on abdominal pain, stool frequency, or stool form. However, since the current literature on the potential role of FMT in treating IBS shows conflicting results, further studies are required. To assess treatment efficacy, we recommend future studies to include daily symptom diaries both before and after treatment intervention.
Keyphrases
- double blind
- abdominal pain
- irritable bowel syndrome
- placebo controlled
- clinical trial
- phase iii
- study protocol
- phase ii
- randomized controlled trial
- systematic review
- case control
- physical activity
- early onset
- stem cells
- high intensity
- climate change
- cell therapy
- combination therapy
- mesenchymal stem cells
- smoking cessation
- patient reported