INOVASIA Study: A Multicenter Randomized Clinical Trial of Pravastatin to Prevent Preeclampsia in High-Risk Patients.
Muhammad Ilham Aldika AkbarMuhammad Alamsyah AzisDeviana Soraya RiuEllen WawengkangErnawati ErnawatiMuhammad Adrianes BachnasSri SulistyowatiErry Gumilar DachlanJohanes Cornelius MoseGus DekkerPublished in: American journal of perinatology (2022)
· This is an open-label multicenter RCT to evaluate pravastatin effect to prevent preeclampsia.. · Pravastatin significantly reduces the risk of preterm preeclampsia (PE) and preterm birth in high risk PE women.. · Pravastatin had a beneficial effect on perinatal outcomes, including Apgar scores and birth weight..
Keyphrases
- preterm birth
- gestational age
- birth weight
- early onset
- pregnancy outcomes
- low birth weight
- end stage renal disease
- chronic kidney disease
- pregnant women
- newly diagnosed
- ejection fraction
- double blind
- weight gain
- cross sectional
- polycystic ovary syndrome
- peritoneal dialysis
- prognostic factors
- preterm infants
- clinical trial
- type diabetes
- patient reported
- insulin resistance