Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice.

Shi-Kun YangAi-Mei LiYa-Chun Han Can-Hui PengNa SongMing YangMing ZhanLing-Feng ZengPan-Ai SongWei ZhangShi-Qi TangHao Zhang

Published in: Oxidative medicine and cellular longevity (2019)

SS31 protected renal tubulointerstitial injury in diabetic mice through a decrease in mitochondrial fragmentation via suppressing the expression of Drp1 and increasing the expression of Mfn1.

Keyphrases

poor prognosis
oxidative stress
signaling pathway
binding protein
long non coding rna