Neurofilament light chain in patients with a concussion or head impacts: a systematic review and meta-analysis.
Eleni KarantaliDimitrios KazisJack McKennaSymela ChatzikonstantinouFivos PetridisIoannis MavroudisPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2021)
Serum NfL levels are higher in all patients suffering from concussion compared to healthy controls. The sports-related concussion was specifically associated with higher levels of NfL. Further studies exploring the use of NfL as a diagnostic and prognostic biomarker in mild TBI and head impacts are needed.