Neurofilament light chain in patients with a concussion or head impacts: a systematic review and meta-analysis.

Eleni KarantaliDimitrios KazisJack McKennaSymela ChatzikonstantinouFivos PetridisIoannis Mavroudis

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2021)

Serum NfL levels are higher in all patients suffering from concussion compared to healthy controls. The sports-related concussion was specifically associated with higher levels of NfL. Further studies exploring the use of NfL as a diagnostic and prognostic biomarker in mild TBI and head impacts are needed.

Keyphrases

mild traumatic brain injury
end stage renal disease
ejection fraction
traumatic brain injury
newly diagnosed
chronic kidney disease
optic nerve
peritoneal dialysis
prognostic factors
high school
cerebrospinal fluid