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Quantitative 99m Tc-albumin colloid nasal mucociliary clearance as an outcome in primary ciliary dyskinesia.

June Kehlet MarthinKim G NielsenJann Mortensen
Published in: ERJ open research (2023)
NMC velocity discriminated highly significantly between patients with PCD and healthy controls. We suggest here a fast and feasible set up for NMC measurements that is easily applicable for any clinical trial involving PCD medication aimed for the nasal compartment, a step before or parallel to conducting clinical trials investigating whole-lung ciliary function in PCD.
Keyphrases
  • clinical trial
  • chronic rhinosinusitis
  • phase ii
  • open label
  • double blind
  • healthcare
  • study protocol
  • high resolution
  • blood flow
  • adverse drug
  • randomized controlled trial
  • electronic health record